Dynamic tests to study liver function.
نویسندگان
چکیده
Two approaches have generally been used to assessing liver function: one is to measure the products of liver synthesis, the other is to monitor hepatic clearance function. The exogenous dyes that can be used to study liver function are sulphobromophthalein (BSF) and indocyanine green (ICG). One valuable way to measure hepatic function is to use non-toxic substances (stains, sugar, drugs) that are selectively metabolized by the liver and determine the rates of metabolism of these substances in vivo. The antipyrine clearance test is the most common and correlates well with the degree of liver damage. The caffeine clearance test is beneficial in severe liver lesions, but practically useless in the case of moderate liver damage. The galactose clearance test can be used early in the clinical course of jaundice to distinguish between hepatocellular disease and biliary obstruction. The MEGX test is useful as a real-time method for quantitatively assessing pre- and post-transplant liver function. In short, quantitative liver function tests are not suitable for use in screening for liver disease. They are more complex to perform and more expensive than conventional biochemical tests, but superior in monitoring the degree of liver dysfunction.
منابع مشابه
Study the Effect of Valeriana Officinalis and Echium Amoenum on the Liver and Renal Function Tests in Rats
Nowadys herbal medicine is marketing without standard toxicological study. Although people believe that herbal medicine do have any toxic effects, there are some reports indicating the toxicity of the herbal medicine. The aim of this investigation is to study the renal and hepatic effects of Echium Amoenum (EA) and Valeriana Officinalis (VO). Percolated extract of these plants with doses of 100...
متن کاملEvaluation of liver and kidney function in favism patients
Backgrounds: G6PD deficiency is the most common enzymopathy of red blood cells. The clinical symptoms of favism are jaundice, hematuria and haemolytic anaemia that seem to affect liver and kidney in long term. Thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a high rate of fava beans cultivation. Methods: This study was performed on favism pa...
متن کاملComparison of the effects of silver nanoparticles and silver cobalt nanoparticles on function tests and liver tissue changes in adult male rats
Objective(s): This study aimed to compare impacts of silver nanoparticles and silver cobalt nanoparticles on the hepatic function tests and changes in liver tissues in adult male rats.Materials and Methods: This study was conducted on 49 adult male Wistar rats, each weighing approximately 180-220 gr. The rats were randomly assigned to seven groups of seven including one control group and six ex...
متن کاملEvaluation of Factors Influencing Liver Function Test in On-Pump Coronary Artery Bypass Graft Surgery
Background: Liver dysfunction during on-pump coronary artery bypass graft surgery (CABG) is a rare complication but is associated with significant morbidity and mortality. The ability to identify high-risk patients may be helpful in planning appropriate management strategies. We aimed to evaluate the factors influencing liver function tests during on-pump CABG.Methods: In 146 patients scheduled...
متن کامل99mTc-GSA liver dynamic SPECT for the preoperative assessment of hepatectomy.
OBJECTIVE The purpose of the present study was to devise a predictive index to predict residual liver function before hepatic resection, using technetium-99m diethylenetriamine-penta-acetic acid-galactosyl human serum albumin (99mTc-GSA) liver dynamic single photon emission computed tomography (SPECT). METHODS Fifty-seven patients with liver disease underwent liver dynamic SPECT with 99mTc-GS...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- European review for medical and pharmacological sciences
دوره 8 1 شماره
صفحات -
تاریخ انتشار 2004